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Table 4 Anthelmintic drugs, their recommended dose, and route of administration for the treatment of hookworms in humans and animals

From: Ancylostoma ceylanicum and other zoonotic canine hookworms: neglected public and animal health risks in the Asia–Pacific region

Anthelmintic drug

Host

Dose

Route of administration

Reference

Albendazole

Human

500 mg

Single administration, Oral

Jourdan et al. (2018)

400 mg

Once daily for 3 days to treat CLM

Blackwell and Vega-Lopez (2001)

Mebendazole

400 mg

Single administration, PO

Jourdan et al. (2018)

100 mg

Taken twice daily for 3 days

Jourdan et al. (2018)

Thiabendazole

1.5 g

Once daily for 3 days to treat CLM

Blackwell and Vega-Lopez (2001)

Pyrantel pamoate

Dog

5 mg/kg

Oral

TroCCAP (2019a)

Cat

20 mg/kg

TroCCAP (2019b)

Pyrantel embonate

Dog

14 mg/kg

Oral

TroCCAP (2019a)

Cat

57.5 mg/kg

TroCCAP (2019b)

Emodepside

Dog

0.45 mg/kg

Oral

TroCCAP (2019a)

Cat

3 mg/kg

TroCCAP (2019b)

Oxantel embonate

Dog

55 mg/kg

Oral

TroCCAP (2019a)

Milbemycin oxime

Dog

0.5 mg/kg

Oral

TroCCAP (2019a)

Cat

2 mg/kg

TroCCAP (2019b)

Moxidectin

Dog

2.5 mg/kg

Topical

TroCCAP (2019a)

Cat

1 mg/kg

TroCCAP (2019b)

Ivermectin

Human

200 μg/kg

Single administration to treat CLM

Vanhaecke et al. (2014)

Dog

0.20 mg/kg

Oral

TroCCAP (2019a)

Cat

0.024 mg/kg

TroCCAP (2019b)

Selamectin

Dog and Cat

6 mg/kg

Topical

TroCCAP (2019b; 2019a)

Fenbendazole

Dog and Cat

50 mg/kg for 3 days

Oral

TroCCAP (2019b; 2019a)

Oxibendazole

Dog

10–20 mg/kg

Oral

TroCCAP (2019a)

Eprinomectin

Cat

0.5 mg/kg

Topical

TroCCAP (2019b)