Table 1 ICA-induced 8 shared differential metabolites

1

7-Dehydrocholesterol

36.177

385.3441977

1.59

2.94

0.003

1.88

2.26

<0.001

2

7-Oxocholesterol

34.835

401.339414

1.61

6.74

0.008

1.86

3.59

0.002

3

Desmosterol

36.73

367.3338581

1.54

3.11

0.008

1.75

2.09

0.003

4

PC (18:1(9Z)/18:1(9Z))

125.466

824.5521835

1.52

1.51

<0.001

1.84

1.48

<0.001

5

PS (18:0/18:1(9Z))

132.1485

788.5423368

1.62

1.84

0.002

2.15

1.78

<0.001

6

N,N-Dimethylaniline

36.52

281.1373045

1.53

1.86

<0.001

1.65

1.87

0.030

7

2-hydroxy-butanoic acid

179.823

103.0396129

1.63

2.01

0.002

1.78

1.51

0.005

8

N2,N2-Dimethylguanosine

180.198

310.1146027

1.76

0.48

<0.001

1.79

0.58

0.003