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Table 1 Characteristic and pathogenicity of staphylococcal superantigen toxins

From: Update on molecular diversity and multipathogenicity of staphylococcal superantigen toxins

Toxin Genetic element Molecular weight (kDa) Super-antigen activity Emetic activity (μg/animal) First reported year
Monkeya Shrewb
SEA Prophage 27.1 + 25 0.3 1963
SEB Chromosome, SaPI3, Plasmid (pZA10) 28.3 + 100 10 1963
SEC1 SaPI 27.5 + 5 NE 1965
SEC2 SaPI 27.6 + NE 1000 1965
SEC3 SaPI 27.6 + < 50 NE 1965
SED Plasmid (pIB485) 26.9 + NE 40 1967
SEE Prophage (Hypothetical location) 26.4 + NE 10 1971
SEG egc1, egc2, egc3, egc4 27.0 + 160–320 200 1998
SEH Transposon (MGEmw2/mssa476seh/Δseo) 25.1 + 30 1000 1994
SEI egc1, egc2, egc3 24.9 + 300–600 1 1998
SElJ Plasmid (pIB485, pF5) 28.6 + NE NE 1998
SEK Prophages, SaPI1, SaPI3, SaPI5, SaPIbov1 25.3 + 100 1000 1998
SEL SaPIn1, SaPIm1, SaPImw2, SaPIbov1 24.7 + 100c 500 2001
SEM egc1, egc2, 24.8 + 100c 100 2001
SEN egc1, egc2, egc3, egc4 26.1 + 100c 1000 2001
SEO egc1, egc2, egc3, egc4, Transposon 26.8 + 100c 500 2001
SEP Prophage (Sa3n) 26.7 + 100c 50 2001
SEQ SaPI1, SaPI3, SaPI5, Prophage 25.2 + 100c 4 2002
SER Plasmid (pIB485, pF5) 27.0 + < 100 < 1000 2003
SES Plasmid (pF5) 26.2 + < 100 20 2008
SET Plasmid (pF5) 22.6 + < 100 1000 2008
SElU egc2, egc3 27.2 + NE NE 2003
SElV egc4 26.7 + NE NE 2006
SElW egc4 27.3 + NE NE 2006
SElX Chromosome 19.5 + NE NE 2011
SElY Chromosome 23.3 +/− 250c 500 2015
SElZ Chromosome 27.4 + NE NE 2015
SE01 Plasmid 26.4 + NE NE 2017
SE02 Chromosome 27.2 + 250c NE 2020
SEl26 SaPI 25.1 + NE NE 2018
SEl27 SaPI 27.1 + NE NE 2018
TSST-1 SaPIs 22.1 + 1981
  1. Notes: +, Positive reaction; NE, not examined; a) oral administration, b) intraperitoneal administration, c) μg/kg body weight. SE staphylococcal enterotoxins; TSST toxic shock syndrome toxin; SaPI S. aureus pathogenicity islands