Table 2 Multi-pathogenicity of SAg toxins in human and animal diseases and the application in vaccines
From: Update on molecular diversity and multipathogenicity of staphylococcal superantigen toxins
Diseases or vaccines | Associated SAgs (SE, SEl or TSST-1) |
|---|---|
Animal diseases | |
 Bovine mastitis | SEC, TSST-1, SEG, SEN, SEO |
 Swine sepsis | SEB, TSST-1 |
 Arthritis and septicemia in poultry | SEA, SEB, SEC, SEQ |
Human diseases | |
 Staphylococcal food poisoning | SEA~SEE, SEH, SE02 etc. |
 Soft tissue infection associated | TSST-1, SEB, SEC |
 Post respiratory viral infection | TSST-1, SEB, SEC, SElX |
 Purpura fulminans | TSST-1, SEB, SEC |
 Kawasaki-like diseases | TSST-1, SEB, SEC |
 Staphylococcal pneumonia | SEB, SEC, TSST-1, SElX |
 Staphylococcal infective endocarditis | SEC, TSST-1 |
 Staphylococcal sepsis | SEA, SEC, TSST-1 |
 Chronic rhinosinusitis | SEA to SEE, SEG to SEO |
 Atopic dermatitis | SEs, TSST-1 |
 Staphylococcal nonmenstrual TSS | TSST-1, SEB, SEC |
 Inflammatory arthritis | SEA, SEB, SEC, TSST-1 |
 Autoimmune diseases | SEB, SEC, SED, TSST-1 |
Vaccines | |
 Vaccine for Saphylococcus infection | Mutant SEC, mutant TSST-1 |
 Vaccine for food poisoning | Mutant SEA |