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Fig. 8 | Animal Diseases

Fig. 8

From: Porcine epidemic diarrhea virus nsp14 inhibits NF-κB pathway activation by targeting the IKK complex and p65

Fig. 8

Schematic diagram of PEDV nsp14 targets IKK complex and p65 to inhibit NF-κB activity. PEDV nsp14 negatively regulates NF-κB signaling pathway by interacting with IKKα/β and p65, which inhibits the phosphorylation of IKKα/β and p65, and nuclear translocation of NF-κB, leading to the decreased expression of early production of proinflammatory cytokines

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Animal Diseases

ISSN: 2731-0442