Fig. 7From: The QseB/QseC two-component system contributes to virulence of Actinobacillus pleuropneumoniae by downregulating apf gene cluster transcriptionSurvival curves and bacteria loads of mice infected with A. pleuropneumoniae. a Survival curves for Balb/c mouse infected with WT S4074, ΔqseBC, ΔapfA, ΔapfB, ΔapfC and ΔapfD strains. Six-week-old Balb/c mice were inoculated WT S4074, ΔqseBC, ΔapfA, ΔapfB, ΔapfC and ΔapfD strains with 5.00 × 106 CFU by intraperitoneal injection, and the survival of mice was monitored for 120 h post-infection. Data were analyzed by log-rank test. b, c The A. pleuropneumoniae load in lung (b) and blood (c) tissues of infected mouse. Each mice was inoculated WT S4074, ΔqseBC, ΔapfA, ΔapfB, ΔapfC and ΔapfD strains with 5.00 × 106 CFU by intraperitoneal injection. *P < 0.05Back to article page