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Table 1 Experiment 1 setup

From: Evaluating α-galactosylceramide as an adjuvant for live attenuated influenza vaccines in pigs

Group

Experimental group

Vaccine

α-GalCer (μg/kg)

Challenge virusc

N

1

Mock – CO99

Vehiclea

Vehicleb

H3N2 CO99

3

2

TX98ΔNS1 + 0μg αGC – CO99

TX98ΔNS1

Vehicle

H3N2 CO99

2

3

TX98ΔNS1 + 10μg αGC – CO99

TX98ΔNS1

10

H3N2 CO99

3

4

TX98ΔNS1 + 50μg αGC – CO99

TX98ΔNS1

50

H3N2 CO99

3

5

TX98ΔNS1 + 100μg αGC – CO99

TX98ΔNS1

100

H3N2 CO99

3

  1. aVirus-free Dulbecco's Modified Eagle's Medium (DMEM)
  2. b50 μL/kg of dimethyl sulfoxide (DMSO) (the volume used to dissolve the 100 μg/kg dose of α-GalCer used in group 5)
  3. c1 x 106 TCID50 H3N2 A/Swine/Colorado/23619/1999 administered intratracheally (i.t.) in 2 mL of DMEM
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Animal Diseases

ISSN: 2731-0442