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Fig. 8 | Animal Diseases

Fig. 8

From: Altered gene expression in human brain microvascular endothelial cells in response to the infection of influenza H1N1 virus

Fig. 8

GSEA plots of enriched KEGG pathways. a GSEA plots indicating the running enrichment score for gene expression signature of ‘cytokine-cytokine receptor interaction’ (NES = 1.89, padj = 0.0001), and its associated top up-regaulted genes (b) visualized in a heatmap, in addition to the GSEA plot for the (c) ‘neuroactive ligand-receptor interaction’ pathway (NES = 1.76, padj = 0.0001) and its associated top activated genes (d). Black bars underneath the graph present the rank positions of genes from the gene set, the green line refers to the enrichment profile. GO, KEGG and GSEA were performed by the R package clusterProfiler; R package DOSE; R package org.HS.eg.db. and visualized by the R package Enrichplot and R package ggplot2

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Animal Diseases

ISSN: 2731-0442