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Table 4 The influence of parity on estimates of vaccine (Brucella abortus A19) effectiveness for preventing abortions

From: A case study investigating the effects of emergency vaccination with Brucella abortus A19 vaccine on a dairy farm undergoing an abortion outbreak in China

Parity

Year

Incidence of abortion (95% CI), %

Relative risk (95% CI)

p value†

Percent vaccine effectiveness (95% CI), %

1st parity

 

2018

22.8 (14.1, 33.6)

1.00 (reference)

0.012

86.7 (4.4, 98.1)

2020

3.0 (0.1, 15.8)

0.13 (0.02, 0.96)

2nd parity

 

2018

30.3 (15.6, 48.7)

1.00 (reference)

0.072

63.3 (0.0, 87.3)

2020

11.1 (3.1, 26.1)

0.37 (0.13, 1.06)

 ≥ 3rd parity

 

2018

8.3 (1.0, 27.0)

1.00 (reference)

0.686

Not applicable

2020

15.6 (5.3, 32.8)

1.88 (0.40, 8.85)

All parities

 

2018

22.1 (15.4, 30.0)

1.00 (reference)

0.013

56.8 (15.8, 77.8)

2020

9.9 (4.9, 17.5)

0.43 (0.22, 0.84)

  1. †Fisher’s exact test; Relative risk, incidence of abortion compared to that in each category