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Table 5 Dosage of FF and DoxHcl in the compound injection for different purposes

From: The dose regimen formulation of doxycycline hydrochloride and florfenicol injection based on ex vivo pharmacokinetic-pharmacodynamic modeling against the Actinobacillus pleuropneumoniae in pigs

Antibacterial activity

Weight dose (mg/kg b.w.)

Healthy

Diseased

 

FF

DoxHcl

FF

DoxHcl

E = 0

1.00

0.27

1.37

1.92

E = −3

4.07

3.57

4.59

5.08

E = −4

7.30

8.32

7.99

8.04

  1. E = 0, −3, −4, respectively represent the target values of AUC24h/MIC under the targets of antibacterial, therapeutic and eradication
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Animal Diseases

ISSN: 2731-0442