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Fig. 4 | Animal Diseases

Fig. 4

From: Preparation of anti-canine interleukin-31 receptor alpha polyclonal antibody and evaluation of its therapeutic effect in canine atopic dermatitis

Fig. 4

Anti-IL-31RA pAbs decreased inflammatory cytokine and Th2 cytokine levels in the skin. The skin levels of inflammatory cytokines were examined with quantitative real-time PCR. A-C Effects of anti-IL-31RA pAbs on IL-6, TNF-α and IL-1β at the mRNA level in skin were determined. D-E Effects of anti-IL-31RA pAbs on IL-4, IL-5 and IL-13 at the mRNA level in skin were determined. Data are expressed as the means ± SDs. **** P < 0.0001 vs. negative control

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Animal Diseases

ISSN: 2731-0442