Skip to main content

Table 2 IC50, IC90 and SI of the extracts against porcine pseudorabies virus

From: Chinese herbal extracts with antiviral activity: evaluation, mechanisms, and potential for preventing PRV, PEDV and PRRSV infections

Substance

Antiviral activity

Selectivity index

IC90 (mg/mL)

IC50 (mg/mL)

CC90/IC90

CC50/IC50

Echinacea

0.22

0.14

 > 44

 > 144

Taraxacum mongolicum

2.06

0.78

 > 4

 > 21

Ilex rotunda thunb

2.42

0.80

 > 1

 > 6

Ilex purpurea hassk

0.42 ± 0.03

0.26 ± 0.10

 > 16

 > 49

Ganoderma lucidum karst (ethanol)

1.09 ± 0.16

0.43 ± 0.09

 > 5.79

 > 21

  1. The cytotoxic concentrations of 50% (CC50) and 90% (CC90); The inhibitory concentrations of 50% (IC50) and 90% (IC90) values of extracts
  2. SI The selectivity index is defined as the ratio of CC50 to IC50 (SI = CC50/IC50), N.d not determined
Back to article page

Animal Diseases

ISSN: 2731-0442