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Table 3 IC50, IC90 and SI of the extracts against porcine epidemic diarrhea virus

From: Chinese herbal extracts with antiviral activity: evaluation, mechanisms, and potential for preventing PRV, PEDV and PRRSV infections

Substance

Antiviral activity

Selectivity index

IC90 (mg/mL)

IC50 (mg/mL)

CC90/IC90

CC50/IC50

Echinacea

0.64

0.13

 > 15

 > 151

Taraxacum mongolicum

N.d

0.28

N.d

 > 60

Ilex rotunda thunb

N.d

0.42 ± 0.05

N.d

 > 13

Ilex purpurea hassk

1.13 ± 0.05

0.67 ± 0.05

 > 6

 > 19

Ganoderma lucidum Karst (ethanol)

N.d

N.d

N.d

N.d

  1. The cytotoxic concentrations of 50% (CC50) and 90% (CC90); The inhibitory concentrations of 50% (IC50) and 90% (IC90) values of extracts
  2. SI The selectivity index is defined as the ratio of CC50 to IC50 (SI = CC50/IC50), N.d not determined
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Animal Diseases

ISSN: 2731-0442