Table 4 Values (mean and standard deviation) of hematological, biochemical, and urinalysis tests of dogs with chronic kidney disease seropositive and seronegative for Leptospira interrogans

Blood count

 Erythrocytes (10⁹/L)

5.5–8

6.68 ± 0.44^†

5.3 ± 1.8^†

5.7 ± 1.8^†

 Hb (gr/dL)

12–18

15.22 ± 1.3^†

14.4 ± 2.7^†

22.4 ± 43.5^†

 Hct (%)

35–57

46.1 ± 5.4^†

42.3 ± 5^†

40.7 ± 10.7^†

 Leukocytes (10⁹/L)

6–16.9

8.7 ± 0.7^†

16.8 ± 6.5^‡

13.3 ± 5.2^†‡

 Platelets (10⁹/L)

200–500

348.7 ± 50.5^†

147 ± 39.2^‡

186.8 ± 76.6^‡

Clinical chemistry

 ALT (U/L)

10–109

33.8 ± 8.4^†

40.2 ± 149.3^‡

111.2 ± 89.7^‡

 AST (U/L)

23–66

29.18 ± 4.1^†

93.5 ± 91.5^‡

100.7 ± 149.3^‡

 Total proteins (gr/dL)

5.4–7.5

6.6 ± 0.5^‡

6.8 ± 0.9^†

5.8 ± 1^‡

 Albumin (gr/dL)

2.3–3.1

2.66 ± 0.2

2.5 ± 0.5

2.8 ± 0.6

 Globulin (gr/dL)

2.7–4.4

3.3 ± 0.3^‡

4.5 ± 0.9^†

3.4 ± 0.7^‡

 Ratio A:G

0.59–1.1

0.84 ± 0.06

0.6 ± 0.2

0.86 ± 0.3

 Total bilirrubin (mg/dL)

0.0–0.3

0.08 ± 0.07^†

1.9 ± 2.7^‡

1.53 ± 3.7^‡

 Urea (mg/dL)

12.8–55.6

16.8 ± 3^†

105.7 ± 51.7^‡

81.1 ± 27.4^‡

 Creatinine (mg/dL)

0.5–1.7

0.7 ± 0.12^†

3.2 ± 1.8^‡

2.2 ± 1^‡

 Phosphor (mg/dL)

2.9–5.3

3.5 ± 0.4^†

5.9 ± 2.6^‡

4.8 ± 2.9^†‡

 Sodium (mEq/L)

142–152

146.5 ± 2.5^†

147 ± 4.2^†

144.6 ± 10.9^†

 Potassium (mEq/L)

3.9–5.1

4.5 ± 0.4^†

5 ± 0.7^†

4.4 ± 0.6^†

Urianalysis

 UD

1.03–1.060

1.033 ± 0.002^†

1.014^‡

1.018^‡

 pH

5–8.5

6.4 ± 0.5

5.9

6.3

 Blood (cel/µL)

Negative

Negative^†

10 ± 23.6^†‡

25.7 ± 60.2^‡

 Proteins (g/L)

Negative

Negative^†

3.08 ± 5.7^‡

3.8 ± 7^‡