Fig. 2

OASL facilitates M. tuberculosis survival in the macrophages. A The protein expression level of OASL in THP-1 cells after M. tuberculosis infection, three repeats were shown for each sample; B–C The OASL knockdown efficiency in THP-1 cells was validated by qRT-PCR and western blot; D The visualization of M. tuberculosis in THP-1 cell lines using the confocal microscope, Scale bars = 10 μm; E The quantification of intracellular bacteria per cell; F Viable intracellular M. tuberculosis in THP-1 cell lines at day 0 and day 3 post-infection. Data presented by mean ± SEM. All experiments were performed in triplicate. The values of *p < 0.05 were considered a statistically significant difference